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Found 6 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50008854'
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008854(2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  3.70nMAssay Description:Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008854(2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  3.70nMAssay Description:Binding affinity against Opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008854(2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  3.70nMAssay Description:Binding affinity towards opioid receptor kappa was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008854(2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  9.60nMAssay Description:Effect on plasma amine oxidase (0.1 uM) after 15 min of incubation at pH 7.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008854(2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  9.60nMAssay Description:Binding affinity for the Opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008854(2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  1.50E+3nMAssay Description:Effect on plasma amine oxidase (0.1 uM) after 0 min of incubation at pH 7.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed