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Found 3 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50090694'
TargetKappa-type opioid receptor(Homo sapiens (Human))
The University Of Bath

US Patent
LigandPNGBDBM50090694(CHEMBL3581740 | US9259422, 22, R = Ph-BU128 | US94...)
Affinity DataKi:  0.0800nM ΔG°:  -57.6kJ/molepH: 7.4 T: 2°CAssay Description:As Alt et al., 2002. Membranes (20 ug) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presence ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
The University Of Bath

US Patent
LigandPNGBDBM50090694(CHEMBL3581740 | US9259422, 22, R = Ph-BU128 | US94...)
Affinity DataKi:  0.0800nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by beta counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The University Of Bath

US Patent
LigandPNGBDBM50090694(CHEMBL3581740 | US9259422, 22, R = Ph-BU128 | US94...)
Affinity DataKi:  0.0800nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In DepthDetails US Patent