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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial' and Ligand = 'BDBM273085'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273085
PNG
((R)-N-benzyl-1-[7-oxo-6-(tetrahydro-2H-pyran-4-yl)...)
Show SMILES FC(F)(F)c1nc2sc(nc2c(=O)n1C1CCOCC1)N1CCC[C@@H]1C(=O)NCc1ccccc1
Show InChI InChI=1S/C23H24F3N5O3S/c24-23(25,26)21-29-19-17(20(33)31(21)15-8-11-34-12-9-15)28-22(35-19)30-10-4-7-16(30)18(32)27-13-14-5-2-1-3-6-14/h1-3,5-6,15-16H,4,7-13H2,(H,27,32)/t16-/m1/s1
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 11n/an/an/an/a8.0n/a



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair