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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial' and Ligand = 'BDBM273139'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial


(Homo sapiens (Human))
BDBM273139
PNG
((R)-N-benzyl-1-(7-oxo-5-trifluoromethyl-6,7-dihydr...)
Show SMILES FC(F)(F)c1nc2sc(nc2c(=O)[nH]1)N1CCC[C@@H]1C(=O)NCc1ccccc1
Show InChI InChI=1S/C18H16F3N5O2S/c19-18(20,21)16-24-14(28)12-15(25-16)29-17(23-12)26-8-4-7-11(26)13(27)22-9-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H,22,27)(H,24,25,28)/t11-/m1/s1
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PC cid
PC sid
UniChem
US Patent
n/an/a 6.90n/an/an/an/a8.0n/a



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...


US Patent US10065972 (2018)

More data for this
Ligand-Target Pair