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Found 7 Enz. Inhib. hit(s) with Target = 'Lanosterol synthase' and Ligand = 'BDBM50128065'
TargetLanosterol synthase(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (Chuv) And University Of Lausanne (Unil

Curated by ChEMBL
LigandPNGBDBM50128065(CHEMBL304858 | CHEMBL324162 | N-allyl-6-(4-(4-brom...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of human liver microsome 2,3-OSC after 1 hr by Silica gel plate phosphor imagingMore data for this Ligand-Target Pair
TargetLanosterol synthase(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (Chuv) And University Of Lausanne (Unil

Curated by ChEMBL
LigandPNGBDBM50128065(CHEMBL304858 | CHEMBL324162 | N-allyl-6-(4-(4-brom...)
Affinity DataIC50:  6.5nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
TargetLanosterol synthase(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (Chuv) And University Of Lausanne (Unil

Curated by ChEMBL
LigandPNGBDBM50128065(CHEMBL304858 | CHEMBL324162 | N-allyl-6-(4-(4-brom...)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
TargetLanosterol synthase(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (Chuv) And University Of Lausanne (Unil

Curated by ChEMBL
LigandPNGBDBM50128065(CHEMBL304858 | CHEMBL324162 | N-allyl-6-(4-(4-brom...)
Affinity DataIC50:  6.5nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase from human liver microsomesMore data for this Ligand-Target Pair
TargetLanosterol synthase(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (Chuv) And University Of Lausanne (Unil

Curated by ChEMBL
LigandPNGBDBM50128065(CHEMBL304858 | CHEMBL324162 | N-allyl-6-(4-(4-brom...)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of human C-terminal His6-tagged OSC expressed in Pichia pastoris GS115 using 2,3-oxidosqualene as substrate after 90 mins by 1H NMR methodMore data for this Ligand-Target Pair
TargetLanosterol synthase(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (Chuv) And University Of Lausanne (Unil

Curated by ChEMBL
LigandPNGBDBM50128065(CHEMBL304858 | CHEMBL324162 | N-allyl-6-(4-(4-brom...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
TargetLanosterol synthase(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (Chuv) And University Of Lausanne (Unil

Curated by ChEMBL
LigandPNGBDBM50128065(CHEMBL304858 | CHEMBL324162 | N-allyl-6-(4-(4-brom...)
Affinity DataIC50:  224nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair