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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Liver X Receptor alpha (LXR-alpha)' and Ligand = 'BDBM20023'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Liver X Receptor alpha (LXR-alpha)


(Homo sapiens (human))
BDBM20023
PNG
(2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...)
Show SMILES OC(=O)C(F)(F)c1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1
Show InChI InChI=1S/C32H21F5N2O3/c33-31(34,30(41)42)22-14-12-19(13-15-22)17-38-23-9-4-8-21(16-23)27-24-10-5-11-26(32(35,36)37)28(24)39-18-25(27)29(40)20-6-2-1-3-7-20/h1-16,18,38H,17H2,(H,41,42)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 30.2n/an/an/an/a7.44



Wyeth Research



Assay Description
Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...


Bioorg Med Chem 15: 3321-33 (2007)

More data for this
Ligand-Target Pair