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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Liver X receptor beta (LXRB)' and Ligand = 'BDBM50172624'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Liver X receptor beta (LXRB)


(Homo sapiens (Human))
BDBM50172624
PNG
(CHEMBL3809494)
Show SMILES CN(C)C(=O)c1ccc(cc1Cl)-c1cnc(N2CCN(CC2)C(=O)[C@](O)(c2ccccc2)C(F)(F)F)c(c1)C#N
Show InChI InChI=1/C28H25ClF3N5O3/c1-35(2)25(38)22-9-8-18(15-23(22)29)20-14-19(16-33)24(34-17-20)36-10-12-37(13-11-36)26(39)27(40,28(30,31)32)21-6-4-3-5-7-21/h3-9,14-15,17,40H,10-13H2,1-2H3/t27-/s2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/an/an/a 8n/an/an/an/a



WuXi AppTec Company, Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at GST-tagged LXRbeta-LBD (unknown origin) by LanthaScreen TR-FRET liver X receptor coactivator assay


J Med Chem 59: 3489-98 (2016)

More data for this
Ligand-Target Pair