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Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50179652'
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50179652(1-(3-cyanophenyl)-3-(1-methyl-4-oxoimidazolidin-2-...)
Affinity DataIC50:  3.40E+3nMAssay Description:Displacement of [3H]MPEP from mGluR5d in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50179652(1-(3-cyanophenyl)-3-(1-methyl-4-oxoimidazolidin-2-...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed