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Found 2 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 8' and Ligand = 'BDBM50173834'
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50173834((R)-4-(3-chloro-4-fluorophenylamino)-6-(1-phenylet...)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity against human Tpl2 kinase via quantification of MEK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50173834((R)-4-(3-chloro-4-fluorophenylamino)-6-(1-phenylet...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human Tpl2 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed