BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Monoamine oxidase' and Ligand = 'BDBM50247673'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoamine oxidase


(Rattus norvegicus (rat))
BDBM50247673
PNG
(2-[1'-Phenyl-3'-(4-methoxyphenyl)-2'-propenylidene...)
Show SMILES COc1ccc(CC=C(N=Nc2nc3ccccc3c(=O)n2C)c2ccccc2)cc1
Show InChI InChI=1S/C25H22N4O2/c1-29-24(30)21-10-6-7-11-23(21)26-25(29)28-27-22(19-8-4-3-5-9-19)17-14-18-12-15-20(31-2)16-13-18/h3-13,15-17H,14H2,1-2H3/b22-17-,28-27+
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.15E+3n/an/an/an/an/an/an/an/a



Hacettepe University

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in rat liver homogenate after 60 mins by Lineweaver-Burk plot


Bioorg Med Chem 17: 675-89 (2009)


Article DOI: 10.1016/j.bmc.2008.11.068
BindingDB Entry DOI: 10.7270/Q2BG2NWT
More data for this
Ligand-Target Pair
Monoamine oxidase


(Rattus norvegicus (rat))
BDBM50247673
PNG
(2-[1'-Phenyl-3'-(4-methoxyphenyl)-2'-propenylidene...)
Show SMILES COc1ccc(CC=C(N=Nc2nc3ccccc3c(=O)n2C)c2ccccc2)cc1
Show InChI InChI=1S/C25H22N4O2/c1-29-24(30)21-10-6-7-11-23(21)26-25(29)28-27-22(19-8-4-3-5-9-19)17-14-18-12-15-20(31-2)16-13-18/h3-13,15-17H,14H2,1-2H3/b22-17-,28-27+
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9.05E+3n/an/an/an/an/an/a



Hacettepe University

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in rat liver homogenate after 60 mins by residual activity plot


Bioorg Med Chem 17: 675-89 (2009)


Article DOI: 10.1016/j.bmc.2008.11.068
BindingDB Entry DOI: 10.7270/Q2BG2NWT
More data for this
Ligand-Target Pair