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Found 1 hit Enz. Inhib. hit(s) with Target = 'Monoamine transporters; Norepininephrine & dopamine' and Ligand = 'BDBM50005547'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoamine transporters; Norepininephrine & dopamine


(Rattus norvegicus (rat))
BDBM50005547
PNG
(Benzoic acid 8-methyl-2-methylcarbamoyl-8-aza-bicy...)
Show SMILES CNC(=O)C1C2CC[C@H](C[C@@H]1OC(=O)c1ccccc1)N2C
Show InChI InChI=1S/C17H22N2O3/c1-18-16(20)15-13-9-8-12(19(13)2)10-14(15)22-17(21)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3,(H,18,20)/t12-,13?,14+,15?/m1/s1
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PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]WIN-35428 binding to the dopamine transporter.


J Med Chem 35: 969-81 (1992)


Article DOI: 10.1021/jm00084a001
BindingDB Entry DOI: 10.7270/Q24T6K0F
More data for this
Ligand-Target Pair