BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1/M5 chimeric protein' and Ligand = 'BDBM50314591'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M1/M5 chimeric protein


(Homo sapiens (Human))
BDBM50314591
PNG
(CHEMBL1092460 | N-(3-chloro-4-(4-ethylpiperazin-1-...)
Show SMILES CCN1CCN(CC1)c1ccc(NC(=O)c2ccccc2OC)cc1Cl
Show InChI InChI=1S/C20H24ClN3O2/c1-3-23-10-12-24(13-11-23)18-9-8-15(14-17(18)21)22-20(25)16-6-4-5-7-19(16)26-2/h4-9,14H,3,10-13H2,1-2H3,(H,22,25)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Antagonist activity at human muscarinic M5 receptor expressed in CHO-K1 cells assessed as inhibition of acetylcholine-induced calcium mobilization


Bioorg Med Chem Lett 20: 2174-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.041
BindingDB Entry DOI: 10.7270/Q2D50N38
More data for this
Ligand-Target Pair