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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM50006600'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50006600
PNG
(5-[4-(Hexane-1-sulfinyl)-[1,2,5]thiadiazol-3-yl]-1...)
Show SMILES CCCCCCS(=O)c1nsnc1C1=CCCN(C)C1
Show InChI InChI=1S/C14H23N3OS2/c1-3-4-5-6-10-20(18)14-13(15-19-16-14)12-8-7-9-17(2)11-12/h8H,3-7,9-11H2,1-2H3
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 109n/an/an/an/an/an/a



Novo Nordisk CNS Division

Curated by ChEMBL


Assay Description
In vitro binding affinity against muscarinic acetylcholine receptor M1 from rat hippocampus, using [3H]-oxotremorine-M (Oxo-M) as radioligand


J Med Chem 35: 2274-83 (1992)


Article DOI: 10.1021/jm00090a019
BindingDB Entry DOI: 10.7270/Q22J69TH
More data for this
Ligand-Target Pair