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Found 7 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM50030223'
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030223(CHEMBL3354068)
Affinity DataKi:  0.912nMAssay Description:Displacement of [3H]NMS from human M1 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030223(CHEMBL3354068)
Affinity DataIC50:  22nMAssay Description:Antagonist activity at human M1 receptor expressed in HEK293T cells assessed as inhibition of carbachol-induced response by BRET based beta-arrestin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030223(CHEMBL3354068)
Affinity DataIC50:  380nMAssay Description:Antagonist activity at human M1 receptor expressed in HEK293T cells assessed as inhibition of carbachol-induced response by BRET based Gq protein eng...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030223(CHEMBL3354068)
Affinity DataIC50:  741nMAssay Description:Antagonist activity at human M1 receptor expressed in HEK293T cells assessed as inhibition of carbachol-induced response by BRET based Gq protein act...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030223(CHEMBL3354068)
Affinity DataEC50:  174nMAssay Description:Agonist activity at human M1 receptor expressed in HEK293T cells by BRET based beta-arrestin engagement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030223(CHEMBL3354068)
Affinity DataEC50:  42nMAssay Description:Agonist activity at human M1 receptor expressed in HEK293T cells by BRET based Gq protein activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030223(CHEMBL3354068)
Affinity DataEC50:  166nMAssay Description:Agonist activity at human M1 receptor expressed in HEK293T cells by BRET based Gq protein engagement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed