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Found 3 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM50326218'
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326218(CHEMBL1242923 | N-{1-[3-(3-Oxo-2,3-dihydrobenzo[1,...)
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity to human muscarinic M1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326218(CHEMBL1242923 | N-{1-[3-(3-Oxo-2,3-dihydrobenzo[1,...)
Affinity DataEC50:  61nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50326218(CHEMBL1242923 | N-{1-[3-(3-Oxo-2,3-dihydrobenzo[1,...)
Affinity DataEC50:  61nMAssay Description:Agonist activity at human M1 receptor expressed in CHO-K1 cells assessed as calcium mobilization for 6 mins by Calcium4-based stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed