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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M2' and Ligand = 'BDBM50111338'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50111338
PNG
(CHEMBL11947 | Furan-2-yl-[4-(4-isopropylsulfanyl-b...)
Show SMILES CC(C)Sc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)c2ccco2)cc1
Show InChI InChI=1S/C25H34N2O2S/c1-19(2)30-23-7-5-20(6-8-23)18-21-9-13-26(14-10-21)22-11-15-27(16-12-22)25(28)24-4-3-17-29-24/h3-8,17,19,21-22H,9-16,18H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
923n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against muscarinic acetylcholine receptor M2 stably expressed in CHO-K1 cells using [3H]-QNB as radioligand.


Bioorg Med Chem Lett 12: 1087-91 (2002)


Article DOI: 10.1016/s0960-894x(02)00096-3
BindingDB Entry DOI: 10.7270/Q2MS3S2P
More data for this
Ligand-Target Pair