Found 14 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Ligand = 'BDBM10759' 
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University Of Arkansas
Curated by PDSP Ki Database
University Of Arkansas
Curated by PDSP Ki Database
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University Of Arkansas
Curated by PDSP Ki Database
University Of Arkansas
Curated by PDSP Ki Database
Affinity DataKi: 4.70E+3nMAssay Description:Displacement of [3H]N-methyl-scopolamine bromide from human recombinant muscarinic M3 receptor expressed in HEK293T cell membranes after 1 hr by liqu...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University Of Arkansas
Curated by PDSP Ki Database
University Of Arkansas
Curated by PDSP Ki Database
Affinity DataKi: 6.76E+3nMAssay Description:Displacement of [3H]N-methyl-scopolamine from human recombinant muscarinic M3 receptor expressed in CHO-FlpIn cells after 6 hrs by liquid scintillati...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University Of Arkansas
Curated by PDSP Ki Database
University Of Arkansas
Curated by PDSP Ki Database
Affinity DataKi: 6.80E+3nMAssay Description:Displacement of [3H]N-methyl-scopolamine from human recombinant muscarinic M3 receptor expressed in CHO-FlpIn cells after 6 hrs by liquid scintillati...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University Of Arkansas
Curated by PDSP Ki Database
University Of Arkansas
Curated by PDSP Ki Database
Affinity DataKi: 7.08E+3nMAssay Description:Displacement of [3H]NMS from human cloned muscarinic M3 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University Of Arkansas
Curated by PDSP Ki Database
University Of Arkansas
Curated by PDSP Ki Database
Affinity DataEC50: 23nMAssay Description:Agonist activity at recombinant human muscarinic M3 receptor expressed in CHO cells assessed as upregulation in ERK1/2 phosphorylation after 5 mins b...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University Of Arkansas
Curated by PDSP Ki Database
University Of Arkansas
Curated by PDSP Ki Database
Affinity DataEC50: 23nMAssay Description:Agonist activity at recombinant human muscarinic M3 receptor expressed in CHO cells assessed as upregulation in ERK1/2 phosphorylation after 5 mins b...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University Of Arkansas
Curated by PDSP Ki Database
University Of Arkansas
Curated by PDSP Ki Database
Affinity DataEC50: 240nMAssay Description:Agonist activity at Gq/11 coupled recombinant human muscarinic M3 AChR expressed in CHO-FlpIn cells assessed as IP-one accumulation after 40 mins by ...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University Of Arkansas
Curated by PDSP Ki Database
University Of Arkansas
Curated by PDSP Ki Database
Affinity DataEC50: 240nMAssay Description:Agonist activity at Gq/11 coupled recombinant human muscarinic M3 AChR expressed in CHO-FlpIn cells assessed as IP-one accumulation after 40 mins by ...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University Of Arkansas
Curated by PDSP Ki Database
University Of Arkansas
Curated by PDSP Ki Database
Affinity DataEC50: 3.20nMAssay Description:Agonist activity at human muscarinic M3 receptor expressed in BHK-21 cells assessed as calcium mobilization for 6 mins by Calcium4-based stainingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University Of Arkansas
Curated by PDSP Ki Database
University Of Arkansas
Curated by PDSP Ki Database
Affinity DataEC50: 220nMAssay Description:Activation of M3-ACh receptor-FLASH/CFP expressed in HEK293 cells assessed as FRET signalMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University Of Arkansas
Curated by PDSP Ki Database
University Of Arkansas
Curated by PDSP Ki Database
Affinity DataEC50: 205nMAssay Description:Agonist activity at human muscarinic M3 receptor expressed in CHO cells after 30 mins by GTPgamma35S binding assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University Of Arkansas
Curated by PDSP Ki Database
University Of Arkansas
Curated by PDSP Ki Database
Affinity DataEC50: 3.20nMAssay Description:Agonist activity at human muscarinic M3 receptor expressed in BHK-21 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
