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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Ligand = 'BDBM50405761'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Cavia porcellus)
BDBM50405761
PNG
(CHEMBL168322)
Show SMILES Clc1cccc(CNCCCCCCNCCCCCCCCNCCCCCCNCc2cccc(Cl)c2)c1
Show InChI InChI=1S/C34H56Cl2N4/c35-33-19-15-17-31(27-33)29-39-25-13-7-5-11-23-37-21-9-3-1-2-4-10-22-38-24-12-6-8-14-26-40-30-32-18-16-20-34(36)28-32/h15-20,27-28,37-40H,1-14,21-26,29-30H2
MMDB

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 2.29E+3n/an/an/an/an/a



University of Camerino

Curated by ChEMBL


Assay Description
Antagonist potency against carbachol induced contractions of isolated guinea pig ileum Muscarinic acetylcholine receptor


J Med Chem 32: 79-84 (1989)


Article DOI: 10.1021/jm00121a017
BindingDB Entry DOI: 10.7270/Q2N017RN
More data for this
Ligand-Target Pair