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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM50042837'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neprilysin


(Rattus norvegicus (Rat))
BDBM50042837
PNG
(6-Mercaptomethyl-5-oxo-1-thia-4-aza-cyclotetradeca...)
Show SMILES OC(=O)[C@@H]1CSCCCCCCCCC(CS)C(=O)N1
Show InChI InChI=1S/C14H25NO3S2/c16-13-11(9-19)7-5-3-1-2-4-6-8-20-10-12(15-13)14(17)18/h11-12,19H,1-10H2,(H,15,16)(H,17,18)/t11?,12-/m0/s1
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MMDB

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Similars

Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Ciba-Geigy Corporation

Curated by ChEMBL


Assay Description
Tested in vitro for the inhibition against neutral endopeptidase (NEP) from rat kidney


J Med Chem 36: 3829-33 (1994)


Article DOI: 10.1021/jm00076a010
BindingDB Entry DOI: 10.7270/Q2125RRG
More data for this
Ligand-Target Pair