Found 3 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-4' and Ligand = 'BDBM50088438' TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
University Of Copenhagen
University Of Copenhagen
Affinity DataKi: 0.720nMAssay Description:Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affiniti...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataIC50: 1.91nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataEC50: 229nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in HEK293 cells assessed as intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
