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Found 3 Enz. Inhib. hit(s) with Target = 'Neuropeptide Y receptor type 1' and Ligand = 'BDBM50065469'
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50065469(2-Diphenylacetylamino-5-guanidino-pentanoic acid 4...)
Affinity DataKi:  4.60nMAssay Description:In vitro binding affinity towards human neuropeptide Y receptor type 1, determined by measuring its ability to displace [125]peptide YYMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50065469(2-Diphenylacetylamino-5-guanidino-pentanoic acid 4...)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of binding of [3H]-propionyl-NPY (1 nM) to Neuropeptide Y receptor type 1 in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50065469(2-Diphenylacetylamino-5-guanidino-pentanoic acid 4...)
Affinity DataIC50:  17nMAssay Description:NPY Y1-antagonistic activity in HEL cells by measuring the inhibition of porcine NPY (10 nM) stimulated increase in the intracellular [Ca2+] concentr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed