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Found 1 hit Enz. Inhib. hit(s) with Target = 'Neutral ceramidase' and Ligand = 'BDBM50428951'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neutral ceramidase


(Homo sapiens)
BDBM50428951
PNG
(CHEMBL2333179)
Show SMILES C[C@@H](NC(=O)CCCCCCCCCCCN(C)C)[C@@H](O)c1ccccc1
Show InChI InChI=1S/C23H40N2O2/c1-20(23(27)21-16-12-11-13-17-21)24-22(26)18-14-9-7-5-4-6-8-10-15-19-25(2)3/h11-13,16-17,20,23,27H,4-10,14-15,18-19H2,1-3H3,(H,24,26)/t20-,23-/m1/s1
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Similars

Article
PubMed
n/an/a 1.20E+5n/an/an/an/an/an/a



Humboldt Universit£t zu Berlin

Curated by ChEMBL


Assay Description
Inhibition of human recombinant neutral ceramidase using Acyl-NBD-C12-cer as substrate after 2 hrs by fluorescence assay


Bioorg Med Chem 21: 874-82 (2013)


Article DOI: 10.1016/j.bmc.2012.12.014
BindingDB Entry DOI: 10.7270/Q29Z9673
More data for this
Ligand-Target Pair