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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nociceptin/mu opioid receptor' and Ligand = 'BDBM50088741'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50088741
PNG
(CHEMBL273404 | N,N-Diethyl-4-({(1R,3R,5S)-8-[2-(4-...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1C[C@@H]2CC[C@H](C1)N2CCc1ccc(F)cc1)c1ccccc1
Show InChI InChI=1S/C32H38FN3O/c1-3-34(4-2)32(37)25-12-16-28(17-13-25)36(27-8-6-5-7-9-27)31-22-29-18-19-30(23-31)35(29)21-20-24-10-14-26(33)15-11-24/h5-17,29-31H,3-4,18-23H2,1-2H3/t29-,30+,31+
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PC sid
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Similars

Article
PubMed
311n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity of the compound was determined by inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 from rat brain membranes


Bioorg Med Chem Lett 10: 1109-11 (2000)


Article DOI: 10.1016/s0960-894x(00)00182-7
BindingDB Entry DOI: 10.7270/Q2X0668B
More data for this
Ligand-Target Pair