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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM203016'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Orexin receptor type 2


(Homo sapiens (Human))
BDBM203016
PNG
(US9242970, 167)
Show SMILES COc1cc(Cl)cc(OC)c1C1CCCC(=O)N1Cc1ccc(OC(F)(F)F)cc1
Show InChI InChI=1/C21H21ClF3NO4/c1-28-17-10-14(22)11-18(29-2)20(17)16-4-3-5-19(27)26(16)12-13-6-8-15(9-7-13)30-21(23,24)25/h6-11,16H,3-5,12H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 28n/an/an/an/an/a37



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
In Vitro Assay: Intracellular Calcium Measurements:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 re...


US Patent US9242970 (2016)


BindingDB Entry DOI: 10.7270/Q2R49PK4
More data for this
Ligand-Target Pair