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Found 6 Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM50292929'
TargetOrexin receptor type 2(Homo sapiens (Human))
Eisai Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50292929(CHEMBL455136 | almorexant)
Affinity DataKi:  4.70nMAssay Description:Displacement of [125I]-Orexin A from human OX2R expressed in CHO cells after 30 mins by topcount analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Eisai Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50292929(CHEMBL455136 | almorexant)
Affinity DataKi:  8nMAssay Description:Binding affinity to orexin receptor 2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Eisai Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50292929(CHEMBL455136 | almorexant)
Affinity DataIC50:  8nMAssay Description:Inhibition of OX2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Eisai Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50292929(CHEMBL455136 | almorexant)
Affinity DataIC50:  8nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as inhibition of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Eisai Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50292929(CHEMBL455136 | almorexant)
Affinity DataIC50:  8nMAssay Description:Antagonist activity at human OX2R expressed in CHO cells assessed as inhibition of orexin-A-induced intracellular calcium releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Eisai Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50292929(CHEMBL455136 | almorexant)
Affinity DataIC50:  8.10E+3nMAssay Description:Antagonist activity at OX2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed