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Found 2 Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 7' and Ligand = 'BDBM50216409'
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50216409(CHEMBL231658 | N-(2-oxo-2-(4-phenethylpiperazin-1-...)
Affinity DataIC50:  39.8nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50216409(CHEMBL231658 | N-(2-oxo-2-(4-phenethylpiperazin-1-...)
Affinity DataIC50:  40nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as effect on intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed