Found 144 Enz. Inhib. hit(s) with Target = 'Peroxisome proliferator-activated receptor gamma' and Ligand = 'BDBM28681' TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Binding affinity for human PPAR gamma construct expressed in bacteria with 3[H] rosiglitazoneMore data for this Ligand-Target Pair
3D Structure (crystal)TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Displacement of [3H]-rosiglitazone from GST-tagged PPARgammaLBD (unknown origin) after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma) was determined by HTRF assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataKi: 47nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...Checked by AuthorMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataKi: 49nMAssay Description:Binding affinity was determined by displacement of 20 nM [3H]- thiazolidinedione from 4 nM biotinylated human peroxisome proliferator-activated recep...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Binding affinity for human peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataKi: 74nM ΔG°: -40.3kJ/molepH: 7.5 T: 2°CAssay Description:The scintillation proximity assay was performed in 96-well plates containing polylysine-coated yttrium silicate beads, His-PPARgamma-LBD, and [3H]ros...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataKi: 74nMAssay Description:Displacement of [3H]rosiglitazone from N-terminal His-tagged human PPARgamma ligand binding domain expressed in Escherichia coli BL21 DE3 cells by sc...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataKi: 120nMAssay Description:Binding affinity to human Peroxisome proliferator activated receptor gamma using scintillation proximity assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataKi: 136nMAssay Description:In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataKi: 136nMAssay Description:Binding affinity towards peroxisome proliferator activated receptor gamma (PPAR gamma)More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataKi: 440nMAssay Description:Displacement of radiolabeled darglitazone from human PPAR gamma by SPA assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataKi: 440nMAssay Description:Displacement of radiolabeled darglitazone from human PPAR gamma by SPA binding assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Initial binding affinity against PPAR-gamma receptorMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Displacement of tritium labeled ligand from human PPARgamma by SPA assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Binding affinity at human peroxidase proliferator activated receptor gamma (hPPARgamma)More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Final binding affinity against PPAR-gamma receptorMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Final binding affinity against PPAR-gamma receptorMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-[porpyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-propyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-propyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-pro-pyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-[propyl-(5-pyridin-2-yl-thiophene-2-sulfonyl)-amino]-propyl}-phenoxy)-propionic acid from human PPARgamma by SPAMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Displacement of [3H]-2-methyl-2-(4-{3-{propyl-(5-pyridin-2-yl-thiophene-2-sulfonyl)-amino}-propyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Displacement of Fluormone from PPAR gammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Displacement of [3H]-rosiglitazone from human PPAR gamma by SPA assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Displacement of [3H]rosiglitazone from human PPAR gamma by SPA assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 199nMAssay Description:Displacement of fluormone PPAR-green from N-terminal His-tagged human PPARgamma-LBD after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human PPARgamma receptor by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:In vitro binding affinity for human PPAR gamma receptor using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Displacement of [3H2]nTZD3 from human recombinant GST-fused PPARgamma expressed in Escherichia coli by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]-rosiglitazone from GST-tagged PPARgammaLBD (unknown origin) after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Displacement of radio-labeled full agonist from PPARgamma receptorMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibitory concentration against human peroxisome proliferator activated receptor gamma in SPA assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:In vitro binding affinity for human PPAR gamma in SPAMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:In vitro binding affinity against human Peroxisome proliferator activated receptor deltaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARgamma by scintillation proximity assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of human peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:In vitro binding affinity against human PPAR gamma (peroxisome proliferator-activated gamma receptor)More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 256nMAssay Description:Displacement of fluorescein labeled ligand from PPARgamma receptor by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 267nMAssay Description:Agonist activity at N-terminal His-tagged human PPARgamma ligand binding domain by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 274nM EC50: 223nMpH: 7.4 T: 2°CAssay Description:Human 6His-PPAR ligand-binding domain was added to the mixture containing radioligand and test compound, followed by yttrium silicate polylysine SPA ...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Receptor binding affinity of the compound to human Peroxisome proliferator activated receptor gamma against [3H]-ragalitazar radioligandMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 450nMAssay Description:Displacement of radio labeled 2(S)-(2-benzoyl-phenylamino)-3-{4-[1,1-ditritio-2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-propionic acid from G...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Initial binding affinity against PPAR-gamma receptorMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataEC50: 40nMAssay Description:The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Cnrs Umr 6052
Curated by ChEMBL
Cnrs Umr 6052
Curated by ChEMBL
Affinity DataKd: 14.8nM EC50: 3.80nMpH: 7.5 T: 2°CAssay Description:Kd values were obtained by incubating His-PPARgamma-LBD with biotinylated peptide, europium-labeled anti-histidine antibody, and allophycocyanin-labe...More data for this Ligand-Target Pair
