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Found 2 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50336878'
LigandPNGBDBM50336878(2-morpholino-N6-(tetrahydro-2H-pyran-4-yl)-4,5'-bi...)
Affinity DataIC50:  13nMAssay Description:Inhibition of PI3Kalpha after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50336878(2-morpholino-N6-(tetrahydro-2H-pyran-4-yl)-4,5'-bi...)
Affinity DataEC50:  220nMAssay Description:Inhibition of PI3Kalpha-mediated Akt phosphorylation at Ser473 in human A2780 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed