BindingDB PrimarySearch

Found 1 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform' and Ligand = 'BDBM50312607'

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Genentech

Curated by ChEMBL

BDBM50312607(5-(6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-...)

IC50: 33nMAssay Description:Inhibition of recombinant PI3Kgamma assessed as PIP3 product formation by fluorescence polarization assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed MMDB
PDB

3D Structure (crystal)