Found 6 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta' and Ligand = 'BDBM25028' TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Monash University (Parkville Campus)
Curated by ChEMBL
Monash University (Parkville Campus)
Curated by ChEMBL
Affinity DataIC50: 590nMAssay Description:Inhibition of human PI3KC2beta by non-radiometric ADP-Glo assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Monash University (Parkville Campus)
Curated by ChEMBL
Monash University (Parkville Campus)
Curated by ChEMBL
Affinity DataIC50: 590nMAssay Description:Inhibition of PI3KC2beta (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Monash University (Parkville Campus)
Curated by ChEMBL
Monash University (Parkville Campus)
Curated by ChEMBL
Affinity DataIC50: 670nMpH: 7.5 T: 2°CAssay Description:Test compounds were added to reaction buffer containing yttrium silicate (Ysi) polylysine SPA beads (Amersham), and the enzyme was added to the assay...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Monash University (Parkville Campus)
Curated by ChEMBL
Monash University (Parkville Campus)
Curated by ChEMBL
Affinity DataIC50: 901nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human PIK3C2B catalytic domain expressed in Baculovirus expression system using PI as substrate prein...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Monash University (Parkville Campus)
Curated by ChEMBL
Monash University (Parkville Campus)
Curated by ChEMBL
Affinity DataKd: 40nMAssay Description:Binding affinity to human PI3KC2beta (M1 to L1634 residues) expressed in mammalian expression system by Kinomescan assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Monash University (Parkville Campus)
Curated by ChEMBL
Monash University (Parkville Campus)
Curated by ChEMBL
Affinity DataKd: 130nMAssay Description:Binding constant for PIK3C2B kinase domainMore data for this Ligand-Target Pair
