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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet activating factor receptor' and Ligand = 'BDBM50003475'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50003475
PNG
(CHEMBL543420 | {4-[2-(2,2-Diphenyl-ethylamino)-ace...)
Show SMILES O=C(CNCC(c1ccccc1)c1ccccc1)N1CCN(CC1)C(C#N)c1cccnc1
Show InChI InChI=1S/C27H29N5O/c28-18-26(24-12-7-13-29-19-24)31-14-16-32(17-15-31)27(33)21-30-20-25(22-8-3-1-4-9-22)23-10-5-2-6-11-23/h1-13,19,25-26,30H,14-17,20-21H2
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Similars

Article
PubMed
n/an/a 220n/an/an/an/an/an/a



J. Uriach& C£a.S.A.

Curated by ChEMBL


Assay Description
Concentration tested in vitro to inhibit PAF-induced maximum aggregation (PAF-Antagonistic activity) by 50%.


J Med Chem 35: 4118-34 (1992)


Article DOI: 10.1021/jm00100a018
BindingDB Entry DOI: 10.7270/Q228087F
More data for this
Ligand-Target Pair