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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet activating factor receptor' and Ligand = 'BDBM50003497'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50003497
PNG
(CHEMBL134123 | {1-[2-(Benzhydryl-amino)-acetyl]-pi...)
Show SMILES O=C(CNC(c1ccccc1)c1ccccc1)N1CCC(CC1)C(C#N)c1cccnc1
Show InChI InChI=1S/C27H28N4O/c28-18-25(24-12-7-15-29-19-24)21-13-16-31(17-14-21)26(32)20-30-27(22-8-3-1-4-9-22)23-10-5-2-6-11-23/h1-12,15,19,21,25,27,30H,13-14,16-17,20H2
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 24n/an/an/an/an/an/a



J. Uriach& C£a.S.A.

Curated by ChEMBL


Assay Description
Concentration tested in vitro to inhibit PAF-induced maximum aggregation (PAF-Antagonistic activity) by 50%.


J Med Chem 35: 4118-34 (1992)


Article DOI: 10.1021/jm00100a018
BindingDB Entry DOI: 10.7270/Q228087F
More data for this
Ligand-Target Pair