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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet activating factor receptor' and Ligand = 'BDBM50003514'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50003514
PNG
(CHEMBL3216401 | CHEMBL545075 | [4-(2-Benzyl-3-phen...)
Show SMILES Cl.Cl.O=C(C(Cc1ccccc1)Cc1ccccc1)N1CCN(CC1)C(C#N)c1cccnc1
Show InChI InChI=1S/C27H28N4O/c28-20-26(24-12-7-13-29-21-24)30-14-16-31(17-15-30)27(32)25(18-22-8-3-1-4-9-22)19-23-10-5-2-6-11-23/h1-13,21,25-26H,14-19H2
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Similars

Article
PubMed
n/an/a 11n/an/an/an/an/an/a



J. Uriach& C£a.S.A.

Curated by ChEMBL


Assay Description
Concentration tested in vitro to inhibit PAF-induced maximum aggregation (PAF-Antagonistic activity) by 50%.


J Med Chem 35: 4118-34 (1992)


Article DOI: 10.1021/jm00100a018
BindingDB Entry DOI: 10.7270/Q228087F
More data for this
Ligand-Target Pair