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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet activating factor receptor' and Ligand = 'BDBM50003546'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50003546
PNG
((4-Pentanoyl-piperazin-1-yl)-pyridin-3-yl-acetonit...)
Show SMILES CCCCC(=O)N1CCN(CC1)C(C#N)c1cccnc1
Show InChI InChI=1S/C16H22N4O/c1-2-3-6-16(21)20-10-8-19(9-11-20)15(12-17)14-5-4-7-18-13-14/h4-5,7,13,15H,2-3,6,8-11H2,1H3
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Similars

Article
PubMed
n/an/a 2.60E+3n/an/an/an/an/an/a



J. Uriach& C£a.S.A.

Curated by ChEMBL


Assay Description
Concentration tested in vitro to inhibit PAF-induced maximum aggregation (PAF-Antagonistic activity) by 50%.


J Med Chem 35: 4118-34 (1992)


Article DOI: 10.1021/jm00100a018
BindingDB Entry DOI: 10.7270/Q228087F
More data for this
Ligand-Target Pair