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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet activating factor receptor' and Ligand = 'BDBM50003553'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50003553
PNG
(CHEMBL544606 | Pyridin-2-yl-[4-(3,4,5-trimethoxy-b...)
Show SMILES COc1cc(cc(OC)c1OC)C(=O)N1CCN(CC1)C(C#N)c1ccccn1
Show InChI InChI=1S/C21H24N4O4/c1-27-18-12-15(13-19(28-2)20(18)29-3)21(26)25-10-8-24(9-11-25)17(14-22)16-6-4-5-7-23-16/h4-7,12-13,17H,8-11H2,1-3H3
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.40E+4n/an/an/an/an/an/a



J. Uriach& C£a.S.A.

Curated by ChEMBL


Assay Description
Concentration tested in vitro to inhibit PAF-induced maximum aggregation (PAF-Antagonistic activity) by 50%.


J Med Chem 35: 4118-34 (1992)


Article DOI: 10.1021/jm00100a018
BindingDB Entry DOI: 10.7270/Q228087F
More data for this
Ligand-Target Pair