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Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor (PDGFr)' and Ligand = 'BDBM50290844'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor receptor (PDGFr)


(Rattus norvegicus)
BDBM50290844
PNG
(6,7-Dimethoxy-4-(3-nitro-phenoxy)-quinoline | CHEM...)
Show SMILES COc1cc2nccc(Oc3cccc(c3)[N+]([O-])=O)c2cc1OC
Show InChI InChI=1S/C17H14N2O5/c1-22-16-9-13-14(10-17(16)23-2)18-7-6-15(13)24-12-5-3-4-11(8-12)19(20)21/h3-10H,1-2H3
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PC cid
PC sid
UniChem

Patents

Article
n/an/a 700n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.


Bioorg Med Chem Lett 7: 2935-2940 (1997)


Article DOI: 10.1016/S0960-894X(97)10117-2
BindingDB Entry DOI: 10.7270/Q20Z738R
More data for this
Ligand-Target Pair