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Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor (PDGFr)' and Ligand = 'BDBM50290854'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor receptor (PDGFr)


(Rattus norvegicus)
BDBM50290854
PNG
(4-(2,6-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Show SMILES COc1cc2nccc(Oc3c(OC)cccc3OC)c2cc1OC
Show InChI InChI=1S/C19H19NO5/c1-21-15-6-5-7-16(22-2)19(15)25-14-8-9-20-13-11-18(24-4)17(23-3)10-12(13)14/h5-11H,1-4H3
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

Article
n/an/a 6.93E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.


Bioorg Med Chem Lett 7: 2935-2940 (1997)


Article DOI: 10.1016/S0960-894X(97)10117-2
BindingDB Entry DOI: 10.7270/Q20Z738R
More data for this
Ligand-Target Pair