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Found 1 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM27150'
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM27150(2-[2-methyl-1-(propan-2-yl)pyrrolidin-2-yl]-1H-1,3...)
Affinity DataKi:  17nM ΔG°:  -43.9kJ/molepH: 8.0 T: 2°CAssay Description:PARP assays utilizing SPA bead-based detection were carried out in 96-well plates. After reaction was terminated, the reaction mixtures were transfer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed