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Found 2 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM27684'
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM27684(2-(4-methoxyphenyl)-1H-1,3-benzodiazole-4-carboxam...)
Affinity DataKi:  6.80nMAssay Description:In vitro inhibition against human full length PARP proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM27684(2-(4-methoxyphenyl)-1H-1,3-benzodiazole-4-carboxam...)
Affinity DataIC50:  60nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP-1 enzyme assay was carried out in reaction mixture consisting of Escherichia coli str...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed