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Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM301928'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM301928
PNG
(US9598396, Compound 5)
Show SMILES CC(Cc1cccc(F)c1)(C#N)c1ccc2c3CCCCc3c(=O)[nH]c2c1
Show InChI InChI=1S/C23H21FN2O/c1-23(14-25,13-15-5-4-6-17(24)11-15)16-9-10-19-18-7-2-3-8-20(18)22(27)26-21(19)12-16/h4-6,9-12H,2-3,7-8,13H2,1H3,(H,26,27)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 0.977n/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...


US Patent US9598396 (2017)

More data for this
Ligand-Target Pair