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Found 2 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM50145091'
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Biomarin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50145091(CHEMBL3763164)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of human PARP1 using [3H]NAD as substrate after 1 min by microplate scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Biomarin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50145091(CHEMBL3763164)
Affinity DataEC50:  15nMAssay Description:Inhibition of PARP in human LoVo cells assessed as inhibition of poly(ADP)-ribose polymerization for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed