Found 2 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid lipoxygenase ALOX15' and Ligand = 'BDBM50123672'
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataKi: 80nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human 15-LOX1 assessed as conversion of linoleic acid to 13(S)-HpODE after 10 mins by UV analysisMore data for this Ligand-Target Pair