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Found 2 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid lipoxygenase ALOX15' and Ligand = 'BDBM50123674'
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50123674(CHEMBL3622740)
Affinity DataKi:  210nMAssay Description:Competitive inhibition of human 15-LOX1 using linoleic acid as substrate after 10 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50123674(CHEMBL3622740)
Affinity DataIC50:  540nMAssay Description:Inhibition of human 15-LOX1 assessed as conversion of linoleic acid to 13(S)-HpODE after 10 mins by UV analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed