Affinity DataIC50: 1nMAssay Description:Inhibition of gamma secretase-mediated amyloid beta42 production in HEK293 cells transfected with human APPSOW and APPLON after 5 hrs by sandwich imm...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of gamma-secretase (unknown origin) expressed in HEK293 cells co-expressing Awe-Lon mutant assessed as reduction of amyloid beta-42 produc...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of gamma secretase-mediated amyloid beta40 production in HEK293 cell membranes transfected with human APPSOW and APPLON mutant after 5 hrs...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of gamma-secretase (unknown origin) expressed in HEK293 cell membrane co-expressing Awe-Lon mutant assessed as reduction of amyloid beta-4...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PS1 gamma-secretase assessed as reduction of amyloid beta-40 production by membrane based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of gamma-secretase (unknown origin) expressed in HEK293 cells co-expressing Awe-Lon mutant assessed as reduction of amyloid beta-40 produc...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of gamma secretase-mediated amyloid beta40 production in HEK293 cells transfected with human APPSOW and APPLON after 5 hrs by sandwich imm...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of PS1 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-40 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of PS1 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as notch cleavageMore data for this Ligand-Target Pair