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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Progesterone receptor' and Ligand = 'BDBM50063116'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Progesterone receptor


(Homo sapiens (Human))
BDBM50063116
PNG
(1,6,8,8,10-Pentamethyl-4-trifluoromethyl-6,7,8,9-t...)
Show SMILES CC1CC(C)(C)Nc2c(C)c3n(C)c(=O)cc(c3cc12)C(F)(F)F
Show InChI InChI=1S/C18H21F3N2O/c1-9-8-17(3,4)22-15-10(2)16-12(6-11(9)15)13(18(19,20)21)7-14(24)23(16)5/h6-7,9,22H,8H2,1-5H3
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Similars

Article
PubMed
n/an/a 2.93E+3n/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Antagonistic activity against human progesterone receptor B (hPR-B) in co-transfected CV-1 cells.


J Med Chem 41: 623-39 (1998)


Article DOI: 10.1021/jm970699s
BindingDB Entry DOI: 10.7270/Q2VM4CZ6
More data for this
Ligand-Target Pair