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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Prolylcarboxypeptidase (PRCP)' and Ligand = 'BDBM193273'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prolylcarboxypeptidase (PRCP)


(Homo sapiens (Human))
BDBM193273
PNG
(US9193762, RS-33-18)
Show SMILES CCCCCNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C23H33N3O4/c1-2-3-7-14-24-21(27)19-12-8-15-25(19)22(28)20-13-9-16-26(20)23(29)30-17-18-10-5-4-6-11-18/h4-6,10-11,19-20H,2-3,7-9,12-17H2,1H3,(H,24,27)/t19-,20-/m0/s1
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

US Patent
2.89E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...


US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Prolylcarboxypeptidase (PRCP)


(Homo sapiens (Human))
BDBM193273
PNG
(US9193762, RS-33-18)
Show SMILES CCCCCNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C23H33N3O4/c1-2-3-7-14-24-21(27)19-12-8-15-25(19)22(28)20-13-9-16-26(20)23(29)30-17-18-10-5-4-6-11-18/h4-6,10-11,19-20H,2-3,7-9,12-17H2,1H3,(H,24,27)/t19-,20-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
5.66E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...


US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair