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Found 2 Enz. Inhib. hit(s) with Target = 'Prostaglandin E synthase' and Ligand = 'BDBM50135226'
TargetProstaglandin E synthase(Mus musculus)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50135226(CHEMBL3747473)
Affinity DataIC50:  60nMAssay Description:Inhibition of mPGES-1 in mouse RAW264.7 cells assessed as reduction in LPS-induced PGE2 production after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50135226(CHEMBL3747473)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PGES-1 in human A549 cell microsomes using PGH2 as substrate assessed as suppression of interleukin-1beta-stimulated PGE2 production in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed