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Found 2 Enz. Inhib. hit(s) with Target = 'Prostaglandin E synthase' and Ligand = 'BDBM50207333'
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50207333(CHEMBL3956753)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50207333(CHEMBL3956753)
Affinity DataIC50:  129nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in interleukin-1 beta-induced PGE2 production incubated for 30 mins followed by IL-1b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed