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Found 7 Enz. Inhib. hit(s) with Target = 'Prostaglandin E synthase' and Ligand = 'BDBM50393042'
TargetProstaglandin E synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393042(CHEMBL2152712)
Affinity DataIC50:  240nMAssay Description:Inhibition of human mPGES-1More data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393042(CHEMBL2152712)
Affinity DataIC50:  241nMAssay Description:Inhibition of human microsomal PGES1 expressed in 293E cells by LC/MS/MS analysisMore data for this Ligand-Target Pair
TargetProstaglandin E synthase(Canis familiaris)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50393042(CHEMBL2152712)
Affinity DataIC50:  555nMAssay Description:Inhibition of mPGES1 in LPS-induced dog whole blood assessed as suppression of PGE2 response pre-incubated for 30 mins followed by LPS addition and m...More data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393042(CHEMBL2152712)
Affinity DataIC50:  740nMAssay Description:Inhibition of mPGES-1 in human whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393042(CHEMBL2152712)
Affinity DataIC50:  744nMAssay Description:Inhibition of mPGES1 in LPS-induced human whole blood assessed as suppression of PGE2 response after 20 to 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393042(CHEMBL2152712)
Affinity DataIC50:  870nMAssay Description:Inhibition of human mPGES-1 assessed as production of PGE2 by cell based assayMore data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393042(CHEMBL2152712)
Affinity DataIC50:  870nMAssay Description:Inhibition of mPGES1 in rhIL-1beta-stimulated human A549 cells assessed as PGE2 level treated for 18 hrs after 30 mins pre-incubation with rhIL-1beta...More data for this Ligand-Target Pair