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Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein-serine O-palmitoleoyltransferase porcupine' and Ligand = 'BDBM50125876'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein-serine O-palmitoleoyltransferase porcupine


(Homo sapiens (Human))
BDBM50125876
PNG
(CHEMBL3623884)
Show SMILES Cn1ncc2cc(NCC(=O)Nc3ccc(cn3)-c3cnccn3)ccc12
Show InChI InChI=1S/C19H17N7O/c1-26-17-4-3-15(8-14(17)10-24-26)22-12-19(27)25-18-5-2-13(9-23-18)16-11-20-6-7-21-16/h2-11,22H,12H2,1H3,(H,23,25,27)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Soochow University

Curated by ChEMBL


Assay Description
Inhibition of porcupine (unknown origin) expressed in mouse L Wnt3A cells co-cultured with TM3 cells harboring luciferase reporter gene assessed as r...


Bioorg Med Chem 23: 6855-68 (2015)


Article DOI: 10.1016/j.bmc.2015.09.048
BindingDB Entry DOI: 10.7270/Q2J10500
More data for this
Ligand-Target Pair